WEDNESDAY, October 26, 2022 (HealthDay News). A study that was published in the Oct. 22, issue of HealthDay News found that monofilament suture doesn’t reduce the rate for singleton pregnancies. The Lancet.
Victoria Hodgetts Morton, Ph.D. from the University of Birmingham in England, and her collaborators conducted a pragmatic, randomized, superiority trial at 75 UK obstetric units. Singleton pregnant women who had a vaginal cerclage were randomly assigned to either a monofilament or braided suture thread for cervical cerclage (1.025 or 1,024, respectively).
The primary outcome was miscarriage, stillbirth or neonatal death within the first week of life. It was determined in 1,003 women in the monofilament and 993 in the braided suture groups, respectively. Researchers found that the rate of pregnancy loss in monofilament and braided suture group women was 8.0 percent and 7.6 percent, respectively (adjusted risks ratio, 1.05, 95 percent confidence interval 0.79 to 1.40).
The authors say that doctors who provide vaginal cervical cerclage to women should use the results of this trial to facilitate discussion around the suture thread and optimize outcomes.
Many authors revealed financial ties to the medical device and biopharmaceutical industries.
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